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It was found out that naltrexone and bupropion combined, which may be marketed later on as Contrave, provide better weight loss results than dieting and exercise alone.
Using two separate drugs to shed weight can be very effective you'll find combinations in front of the FDA now awaiting approval. When dealing with fat loss and the people who go through it you should err along the side of caution and allow the FDA do its job and demand some investigation be done so the public knows the side effects and risks of the medications before we bring them. Keep in mind that drug companies come in business to earn money and that they would say almost anything to keep people on his or her medications.
Researchers discovered that participants taking this drug to get a year, lost excess weight within four weeks and have kept the weight off through the 56 weeks of the study. Contrave can be a combination from the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which are made up of more than one active ingredient, which might make them more effective and safer.
Combo-pilling may be the newest fad or even better the newest into the future under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills has become popular will be the fact that at the time of right now there aren't long term prescription weightloss pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be authorized by the FDA.
Seizures really are a side effect with Contrave and must not be taken in those with seizure disorders. The drug could also raise blood pressure levels and pulse rate, and must not be used in those with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.
The FDA also warned that Contrave can raise blood pressure and heartbeat and must 't be used in patients with uncontrolled high blood pressure, along with by a person with heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients which has a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients towards the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation.
Approving a drug with this particular many potentially lethal unwanted side effects is inconsistent with the mission statement of the FDA. The power from the drug manufacturing lobby is blatantly evident inside the approval of several drugs requiring 'post-marketing' studies which might be clearly significant to overall drug safety within the US.