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    Researchers found that participants using this drug for any year, dropped a few pounds within a month and have kept the load off through the 56 weeks with the study. Contrave is a combination of the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs that are made up of many active ingredient, that might make them more potent and safer.

    Combo-pilling is the newest fad or also the newest ahead under scrutiny and thus it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills has become popular may be the fact that as of right now there aren't any long term prescription weight loss supplements that have been licensed by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be approved by the FDA.

    Seizures can be a side effect with Contrave and really should not be taken in individuals with seizure disorders. The drug could also raise blood pressure levels and pulse rate, and really should not be used in those with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise blood pressure level and heart rate and must not be used in patients with uncontrolled high blood pressure level, in addition to by you are not heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients which has a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients for the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking.

    The most common negative effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.