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  • The Promises Treatment Centers, estimates that between five and 10 percent of the patients at his centers are helped by naltrexone. Those most likely to receive it are people who have a history of early relapse—whoever has been treated before and have not had time to maintain sobriety for considerably more than 1 month.

    Using two separate drugs to lose weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight reduction and the those who go through it one should err along the side of caution and permit the FDA do its job and demand some research be done in order that the public understands the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to generate money and that they would say anything to keep people on their own medications.

    Researchers found out that participants using this drug for the year, dropped a few pounds within 4 weeks and have kept the load off during the entire 56 weeks in the study. Contrave is a combination with the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which might be made up of several active ingredient, which may make them more potent and safer.

    Combo-pilling could be the newest fad or better yet the newest ahead under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular could be the fact that by right now there aren't long term prescription weight loss supplements that have been licensed by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be licensed by the FDA.

    Seizures can be a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug may also raise blood pressure level and heartbeat, and must not be used in people who have a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise blood pressure and heartbeat and must not be used in patients with uncontrolled high blood pressure level, and also by a person with heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients using a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients to the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation.

    "There were no warning signs of depression or suicidal thoughts in trial participants," said Fujioka.