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  • The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment option for chronic weight loss in addition to a reduced-calorie diet and exercise.

    Using two separate drugs to lose weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight reduction and the those who go through it one should err assisting caution and let the FDA do its job and demand some study be done in order that the public recognizes the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies come in business to earn money and that they would say anything to keep people on the medications.

    Researchers found that participants using this drug to get a year, lost excess weight within 4 weeks and have kept the load off throughout the 56 weeks in the study. Contrave is a combination with the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs which might be made up of more than one active ingredient, which may make them more potent and safer.

    Combo-pilling may be the newest fad or in addition to this the newest ahead under scrutiny and thus it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills has become popular could be the fact that as of right now there are no long term prescription weight loss supplements that have been licensed by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be approved by the FDA.

    Seizures are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug also can raise blood pressure and heart rate, and really should not be used in people who have a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure and heartrate and must stop used in patients with uncontrolled high blood pressure levels, in addition to by anyone with heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients having a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients on the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking.

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