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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight reduction in addition to a reduced-calorie diet and physical exercise.
Using two separate drugs to shed weight can be very effective there are combinations before the FDA now awaiting approval. When dealing with weight loss and the people that go through it you ought to err to the side of caution and allow FDA do its job and demand some research be done so that the public knows the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies will be in business to generate income and that they would say anything to keep people on his or her medications.
Researchers discovered that participants investing in this drug to get a year, dropped excess weight within 4 weeks and have kept the body weight off through the entire 56 weeks from the study. Contrave is a combination from the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which are made up of more than one active ingredient, that might make them more potent and safer.
Combo-pilling is the newest fad or also the newest to come under scrutiny and thus it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills is now popular is the fact that by right now there aren't long term prescription slimming capsules that have been approved by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be licensed by the FDA.
Seizures are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug could also raise blood pressure levels and heartrate, and shouldn't be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug.
The FDA also warned that Contrave can raise hypertension and heart rate and must not used in patients with uncontrolled high hypertension, and also by you are not heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients to the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking.
The most common negative effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.