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  • The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment choice for chronic weight loss in addition to a reduced-calorie diet and physical exercise.

    Using two separate drugs to shed pounds can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the those who go through it you need to err assisting caution and let the FDA do its job and demand some study be done so the public knows the side effects and risks of the medications before we bring them. Keep in mind that drug companies are in business to make money and that they would say anything to keep people on their medications.

    Researchers found out that participants using this drug to get a year, lost weight within four weeks and have kept the weight off through the 56 weeks with the study. Contrave is a combination in the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which might be made up of multiple active ingredient, which may make them far better and safer.

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    Seizures really are a side effect with Contrave and must not be taken in people with seizure disorders. The drug could also raise blood pressure levels and heartrate, and mustn't be used in people who have a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug.

    The FDA also warned that Contrave can raise hypertension and heartrate and must 't be used in patients with uncontrolled high hypertension, in addition to by you are not heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients with a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients for the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking.

    The most common unwanted effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.

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    Researchers found out that participants using this drug for a year, dropped a few pounds within 4 weeks and have kept the weight off throughout the 56 weeks from the study. Contrave is really a combination in the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs which can be made up of several active ingredient, that might make them more potent and safer.

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    Seizures can be a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug may also raise hypertension and pulse rate, and mustn't be used in those with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug.

    The FDA also warned that Contrave can raise blood pressure level and pulse rate and must not be used in patients with uncontrolled high hypertension, as well as by you are not heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients to the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking.

    From a psychiatric viewpoint, evidence implies that the ordinary neural mechanism for goal-directed behavior may be hijacked from the addiction, and malfunctions in such a way that its ordinary functions are exaggerated and fixated on its object. An object produces a stimulus as well as the person engages in a "goal-directed behavioral response" that generates a "natural high"(Bostwick & Bucci, 2008).

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  • The U.S. Food and Drug Administration has approved the use of Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) to help manage chronic obesity in older adults with a body mass index (BMI) of more than 27, provided they also have problems with weight-related medical issues such as Tupe2 diabestes, high cholesterol and/or hypertension (blood pressure).Contrave can be a combination of two FDA-approved drugs, naltrexone and bupropion, in a extended-release formulation. Naltrexone qualifies to treat alcohol and opioid dependence. Bupropion qualifies to treat depression and seasonal affective disorder in addition to being an aid to stop smoking treatment.'Obesity continues to be a major public health concern,' said Jean-Marc Guettier, M.D., director of the Division of Metabolism and Endocrinology Products in FDA's Center for Drug Evaluation and Research. 'When used as directed in combination with a healthy lifestyle that includes a reduced-calorie eating and working out, Contrave provides another treatment option for chronic weight loss for people who are obese or are overweight and also have at least one weight-related health.'The drug's effectiveness was evaluated in multiple numerous studies that included approximately 4,500 obese and overweight patients with and without significant weight-related conditions treated for starters year. All patients received lifestyle modification that was comprised of a reduced- calorie diet and regular physical activity. Results from a medical trial that enrolled patients without diabetes demonstrated that patients had a typical weight loss of four years old.1% as opposed to participants who were given placebos) after a 12- month period, while a separate study involving patients with diabetes type 2 had a typical weight loss of 2% over treatment with placebo at 12 months.

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    Seizures are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug also can raise blood pressure levels and heart rate, and really should not be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug.

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  • With everything that individuals deal with to lose weight, diets that won't work, diet pills that won't do what they are supposed to, overpriced digital cameras, in order to name a few. It is no wonder that now the latest idea is to unite prescription medications in the hopes that using the combination may have the miraculous results that they can so desperately want and in some cases need.

    Using two separate drugs to lose weight can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the those who go through it you ought to err to the side of caution and allow FDA do its job and demand some research be done in order that the public recognizes the side effects and risks of the medications before we take them. Keep in mind that drug companies will be in business to generate money and that they would say anything to keep people on the medications.

    Researchers discovered that participants taking this drug for the year, dropped excess weight within 4 weeks and have kept the load off through the 56 weeks with the study. Contrave is often a combination of the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs that are made up of many active ingredient, that might make them more effective and safer.

    Combo-pilling could be the newest fad or also the newest into the future under scrutiny and therefore it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular may be the fact that as of right now there are not any long term prescription weight loss supplements that have been approved by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations happen to be rejected or have yet to be licensed by the FDA.

    Seizures can be a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug may also raise blood pressure level and heartrate, and shouldn't be used in people who have a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise hypertension and pulse rate and must not be used in patients with uncontrolled high blood pressure level, as well as by you aren't heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients using a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients towards the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking.

    "This may be the first drug I'm aware of that targets the two appetite and reward centres inside brain," he said.

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  • A new weight-loss drug that contains anti-addiction drug naltrexone has become approved by the U.S. Food and Drug Administration today, the business said in the statement.

    Using two separate drugs to lose weight can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with fat loss and the people that go through it one should err on the side of caution and let the FDA do its job and demand some study be done in order that the public understands the side effects and hazards of the medications before we bring them. Keep in mind that drug companies will be in business to generate income and that they would say anything to keep people on the medications.

    Researchers discovered that participants taking this drug for any year, lost weight within four weeks and have kept the extra weight off during the entire 56 weeks in the study. Contrave is a combination from the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs which can be made up of more than one active ingredient, which may make them more effective and safer.

    Combo-pilling is the newest fad or in addition to this the newest in the future under scrutiny and so it is just more publicly known lately, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills has become popular is the fact that by right now there are not any long term prescription diet pills that have been approved by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be approved by the FDA.

    Seizures are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug also can raise blood pressure and heartrate, and must not be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure and heartrate and must not be used in patients with uncontrolled high hypertension, and also by you are not heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients using a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients towards the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking.

    "This may be the first drug I'm mindful of that targets both appetite and reward centres in the brain," he said.

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  • On September 26, UCLA researcher reported the outcome of a study, which indicated that Asians who are struggling with alcoholism will benefit especially from naltrexone, considered one of three medications approved by the U.S. Food and Drug Administration (FDA) to the treatment of alcoholism. Recent research has discovered that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a particular mutation that makes them planning to benefit from naltrexone, weighed against about 20% of Caucasians and much less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director from the UCLA Addictions Laboratory. The findings are currently available online ( within the journal Neuropsychopharmacology and will also be published in the upcoming print edition from the journal.

    Using two separate drugs to lose weight can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight-loss and the people that go through it you ought to err assisting caution and allow FDA do its job and demand some study be done in order that the public is aware of the side effects and perils associated with the medications before we take them. Keep in mind that drug companies have been in business to generate income and that they would say almost anything to keep people on their own medications.

    Researchers discovered that participants using this drug for any year, lost excess weight within 4 weeks and have kept the weight off through the entire 56 weeks from the study. Contrave can be a combination with the drugs naltrexone and bupropion, which seems to reflect a fresh trend of weight-loss drugs that are made up of more than one active ingredient, which may make them more efficient and safer.

    Combo-pilling will be the newest fad or better yet the newest ahead under scrutiny and therefore it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular will be the fact that at the time of right now there aren't long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be approved by the FDA.

    Seizures certainly are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug also can raise blood pressure level and heartbeat, and really should not be used in people with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

    The FDA also warned that Contrave can raise blood pressure levels and heartrate and must stop used in patients with uncontrolled high blood pressure, along with by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients with a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients to the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking.

    --Participating in support groups that help the family from the addict recover (such as Al-Anon or Nar-Anon).

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